The PaleoDiet score included six food groups that are encouraged in this diet (fruit, nuts, vegetables, eggs, meat, and fish) and five that are avoided (cereals and grains, dairy products, legumes, culinary ingredients, and processed/ultra-processed foods). A recent prospective cohort study found a significant inverse association between the PaleoDiet score and CVD in the Seguimiento Universidad de Navarra (SUN) cohort. They also found a weaker association that became non-significant was observed when the item for low consumption of ultra-processed foods was removed from the score. These findings suggest that the PaleoDiet may have cardiovascular benefits in participants from a Mediterranean country. Avoidance of ultra-processed foods seems to play a key role in this inverse association. Please share your thoughts and experiences!