Vitamin E has been widely studied as not only an antioxidant but also a significant role in the modulator of signal transduction and regulator of gene expression, to promote heart health and reduce CVD risk.

A recent study reviewed the antioxidant effect of vitamin E and CVD risk in women with obesity. It presented that women with comorbidities such as obesity, polycystic vary syndromes and non-alcoholic fatty liver disease had poor antioxidant status and increased their cardiovascular risk, while vitamin E intake seems to be closely related to risk decreased. Vitamin E intake from food is also inversely associated with mortality from coronary heart disease among postmenopausal and overweight women. This suggested that vitamin E could be considered an additional element of CVD prevention. However, the evidence focusing on vitamin E supplements for female-specific cardiovascular risk is still insufficient.  

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